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Prof. Dr. med. Chr. Woiciechowsky



1.    Woiciechowsky C, Buchholz P, Halle E, Jänisch W, Vogel S: Die Tuberkulose des ZNS - eine wieder aktuelle neurochirurgische Erkrankung. Zentralbl Neurochir 55:71-78, 1994.

2.    Woiciechowsky C, Vogel S, Lehmann R, Staudt J: Transcallosal removal of lesions affecting the third ventricle. An anatomical and clinical study. Neurosurgery 36:117-123, 1995.

3.    Wociechowsky C, Guilarte T, May Ch, Vesper J, Wagner HN Jr., Vogel S: Intrastriatal dopamine infusion reverses compensatory increases in D2 dopamine receptors in the 6-OHDA lesioned rat. Neurodegeneration 4:161-169, 1995.

4.    Wociechowsky C, Vogel S, Meyer R, Lehmann R: Magnetic resonance imaging of a glioblastoma of the optic chiasm. J. Neurosurg 83:923-925, 1995.

5.    Asadullah K, Woiciechowsky C, Liebethal C, Doecke WD, Volk HD, Vogel S, v. Baehr R: Immunodepression following neurosurgical procedures. Crit Care Med 23:1976-1983, 1995.

6.    Asadullah K, Woiciechowsky C, Doecke WD, Egerer, K., Kox W, Vogel S, Sterry W, Volk HD: Very low monocytic HLA-DR expression indicates high risk of infection - immunmonitoring for patients after neurosurgery and patients during high dose steroid therapy. Eur J Ermegency Med 2:184-190, 1995.

7.    Woiciechowsky, C: Glioblastoma of the optic chiasm. J. Neurosurg 84:899, 1996 (Comment).

8.    Woiciechowsky C, Asadullah K., Nestler D, Glöckner F, Volk HD, Vogel S: Different release of cytokines into the cerebrospinal fluid following surgery for intra- and extra-axial brain tumors. Acta Neurochir 139:619-624, 1997.

9.    Woiciechowsky C, Vogel S, Meyer BU, Lehmann R: Neuropsychological and neurophysiological consequences of partial callosotomy. J Neurosurg Sci 41:75-80, 1997.

10.    Meyer BU, Röricht S, Woiciechowsky C: Topography of fibers in the human corpus callosum mediating interhemispheric inhibition between the motor cortices. Ann Neurol 43:360-369, 1998.

11.    Woiciechowsky C, Asadullah K, Nestler D, Schöning B, Glöckner F, Döcke WD, Vogel S, Volk HD: Diminished monocytic HLA-DR expression and ex vivo cytokine secretion capacity in patients with glioblastoma: Effect of tumor extirpation. J Neuroimmunol 84:164-171, 1998.

12.    Röricht S, Meyer BU, Woiciechowsky C, Lehmann R: Callosal and corticospinal tract function in patients with hydrocephalus: a morphometric and transcranial magnetic stimulation study. J Neurol 245:280-288, 1998.

13.    Woiciechowsky C, Asadullah K, Nestler D, Eberhardt B, Platzer C, Schöning B, Glöckner F, Lanksch WR, Volk HD Döcke WD: Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nature Med 4:808-813, 1998.

14.    Woiciechowsky C, Schöning B, Daberkow N, Asche, K., Stoltenburg G, Lanksch WR, Volk HD: Brain-IL-1beta induces local inflammation but systemic ant-inflammatory response through stimulation of both hypothalamic-pituitary-adrenal axis and sympathetic nervous system. Brain Research 816:563-571, 1999.

15.    Woiciechowsky C, Schöning B, Daberkow N, Asche, K., Stoltenburg G, Lanksch WR, Volk HD: Brain-IL-1beta increases neutrophil and decreases lymphocyte counts through stimulation of neuroimmune pathways. Neurobiol Dis 6:200-208, 1999.

16.    Woiciechowsky C, Schöning B, Lanksch WR, Volk HD, Döcke WD: Mechanisms of brain-mediated systemic anti-inflammatory response syndrome causing immunodepression. J Mol Med 77:769-780, 1999.

17.    Schöning B, Elepfandt P, Lanksch WR, Volk HD, Woiciechowsky C: Continuous infusion of pro-inflammatory cytokines into the brain to study brain cytokine induced local and systemic immune effects. Brain Res Protoc 4 :217-222, 1999.

18.    Woiciechowsky C, Schöning B, Lanksch WR, Volk HD Döcke WD: Catecholamine-induced interleukin-10 release – a key mechanism in systemic immunodepression after brain injury. Crit Care 3:R107-R111, 1999.

19.    Herrllinger U, Woiciechowsky C, Quinones A, Sena-Esteves M, Aboody K, Jacobs AH, Rainov NG, Snyder E, Breakefield XO: Neural precursor cells for delivery of replication-conditional HSV-1 vectors to intracerebral gliomas. Mol Ther 1:347-357, 2000.

20.    Stover JF, Schoning B, Beyer TF, Woiciechowsky C, Unterberg AW: Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-alpha in relation to brain edema and contusion following controlled cortical impact injury in rats. Neurosci Lett 288:25-28, 2000.

21.    Herrlinger U, Jacobs A, Quinones A, Woiciechowsky C, Sena-Esteves M, Rainov NG, Fraefel C, Breakefield XO: Helper virus-free herpes simplex typ 1 amplicon vectors for granulocyte-macrophage colony-stimulating factor-nhanced vaccination therapy for experimental glioma. Hum Gene Ther 11:1429-1438, 2000.

22.    Woiciechowsky C, Rupprecht S, Döcke WD, Volk HD: Role of the sympathetic nervous system and the hypothalamic pituitary adrenal axis in brain-mediated compensatory anti-inflammatory response. Biomed Rev 11:29-38, 2000.

23.    Herrlinger U, Pechan PA, Jacobs AH, Woiciechowsky C, Rainov NG, Fraefel C, Paulus W, Reeves SA: HSV-1 infected cell proteins influence tetracycline-regulated transgene expression. J Gene Med 2:379-389, 2000.

24.    Woiciechowsky C: Temozolomid beim Rezidiv eines anaplastischen Astrozytoms und Glioblastoms. Onkologie Service aktuell 1:7-8, 2001.

25.    Stover JF, Schöning B, Sakowitz OW, Woiciechowsky C, Unterberg AW: Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats. J Neurosurg 94:782-787, 2001.

26.    Stockhammer F und Woiciechowsky C: Genetik von Hirntumoren. Brainstorm 2:14-17, 2002.

27.    Elepfandt P, Rupprecht S, Schöning-Burkhardt B, Volk HD, Woiciechowsky C: Oligodeoxynucleotides induce brain inflammtion when infused intracerebroventricularly. Neurosci Lett 322:107-110, 2002.

28.    Woiciechowsky C, Schöning B, Cobanov, J. Lanksch WR, Volk HD Döcke WD: Early IL-6 plasma concentrations correlate with severity of brain injury and pneumonia in brain-injured patients. J Trauma 52:339-345, 2002.

29.    Schöning B, Elepfandt P, Daberkow N, Rupprecht S, Volk HD, Woiciechowsky C: Differences in the granulocyte and monocyte recruitment into the cerebrospinal fluid and brain parenchyma resulting from cerebral infusion of pro-inflammatory cytokines. Neurol Sci 23:211-218, 2002.

30.    Kalbhenn Th, Mittelmeier T, Woiciechowsky C: Late neurological deterioration 30 years following conservative treatment of a lower cervical spine fracture – a case report. Zentralbl Neurochir 63:77-80, 2002.

31.    Stover JF, Sakowitz OW, Schoning B, Rupprecht S, Woiciechowsky C, Unterberg AW: Norepinephrine infusion increases interleukin-6 in plasma and cerebrospinalfluid of brain-injured rats. Med Sci Monit 9:BR382-388, 2003.

32.    Frewert S, Stockhammer F, Zenclussen A, Woiciechowsky C: Intratumoral infusion of IL-1beta and IFN-gamma increases tumor immune cell invasion in a rat glioma model. Neurosci Lett 364:145-148, 2004.

33.    Woiciechowsky C, Schöning B, Stoltenburg G, Stockhammer F und Volk HD: Brain-IL-1beta induces astrogliosis through induction of IL-6: Inhibition by propranolol and IL-10. Med Sci Monit 10:BR325-330, 2004.

34.    Mutlu L, Woiciechowsky C, Bachmann I: Inflammatory response after neurosurgery. Best Pract Res Clinical Anesthesiol 18:407-424, 2004.

35.    Schlosser HG, Kerner T, Woiciechowsky C, Benndorf G: Multiple cerebral Aneurysms and Subarachnoid Hemorrhage in a Patient with Alagille Syndrome – Should screening for cerebral vascular malformation be performed routinely in Alagille patients? AJNR 25:1366-1367, 2004.

36.    Woiciechowsky C, Thomale U, Kroppenstedt S: Degenerative spondylolisthesis of the cervical spine – symptoms and surgical strategies depending ondisease progress. Eur J Spine 13:680-684, 2004.

37.    Woiciechowsky C, Thomale U, Kroppenstedt S: ProSpace PEEK: First experience with a radiolucent PLIF cage (Prospace PEEK). Backup 1:12-13, 2005.

38.    Zenclussen AC, Sollwedel A, Zambon Bertoja A, Gerlof K, Zenclussen ML, Woiciechowsky C, Volk HD: Heme oxygenase as a therapeutic target in immunological pregnancy complications. Int Immunopharmacol 5:41-51, 2005.

39.    Bortoja AZ, Zenclussen ML, Wollenberg I, Paeaschke S, Sollwedel A, Gerlof K, Woiciechowsky C, Volk HD, Zenclussen AC: Upregulation of Bcl-2 at the foetal-maternal interface from mice undergoing abortion. Scand J Immunol. 61:492-502, 2005.

40.    Woiciechowsky C: Distractable Vertebral Cages for Reconstruction after Cervical Corpectomy. Spine 30:1736-1741, 2005.

41.    Cramer P, Thomale U, Okuducu, AF, Lemke AJ, Stockhammer F, Woiciechowsky C: An atypical spinal meningioma with CSF metastasis – fatal progression despite aggressive treatment. J  Neurosurg Spine 3;153-158, 2005.

42.    Sollwedel A, Bertoja AZ, Zenclussen ML, Gerlof K, Lisewski U, Wafula P, Sawitzki B, Woiciechowsky C, Volk HD, Zenclussen AC: Protection from abortion by heme oxygenase-1 up-regulation is associated with increased levels of Bag-1 and neuropilin-1 at the fetal-maternal interface. J Immunol 175:4875-4885, 2005.

43.    Woiciechowsky C, Volk HD: Increased intracranial pressure induces a rapid systemic interleukin-10 release through activation of the sympathetic nervous system. Acta Neurochir Suppl 95:373-376, 2005.

44.    Thomale UW, Kneisler M, Hein A, Metzig M, Lüth T, Woiciechowsky C: A spine frame for intra-operative fixation to increase accuracy in spinal navigation and robotics. Comput Aided Surg 10:151-155, 2005.

45.    Bortoja AZ, Zenclussen ML, Casalis PA, Sollwedel A, Schumacher A, Woiciechowsky C, Volk HD, Zenclussen AC: Anti-P- and E-selectin therapy prevents abortion in the CBA/J x DBA/2J combination by blocking the migration of Th1 lymphocytes into the foetal-maternal interface. Cell Immunol 238:97-102, 2005.

46.    Wurm RE, Kuczer, DA, Schlenger L, Matnjani G, Scheffler D, Cosgrove VP, Ahlswede J, Woiciechowsky C, Budach V. Hypofractionated stereotactic radiotherapy combined with topotecan in recurrent malignant glioma. Int J Radiation Oncology Biol Phys 66 Supp 4:S26-S32, 2006.

47.    Binder D, Temmesfeld-Wollbruck B, Wurm R, Woiciechowsky C, Schaper C, Schurmann D, Suttorp N, Beinert T: [Brain metastases of lung cancer]. Dtsch Med Wochenschr 131:165-171, 2006.

48.    Schmid M, Sollwedel A, Thuere C, Wafula PO, Zenclussen ML, Muller DN, Gratze P, Woiciechowsky C, Volk HD, Zenclussen AC: Murine Pre-Eclampsia Induced by Unspecific Activation of the Immune System Correlates with Alterations in the eNOS and AT1 Receptor Expression in the Kidneys and Placenta. Placenta, 2006.

49.    Schlosser HG, Volk HD, Splettstosser G, Brock M, Woiciechowsky C: A new qualitative interleukin-6 bedside test can predict pneumonia in patients with severe head injury--comparison to the standard Immulite test and a semiquantitative bedside test. J Neurosurg Anesthesiol 19:5-9, 2007.

50.    Woiciechowsky C: Implantation of a distractible titanium cage after cervical corpectomy: technical experience in 20 consecutive cases, by M. Payer, Volume 148, Issue 11, November 2006, Pages 1173-1180. Acta Neurochir (Wien), 149:213; author reply 213-4, 2007.

51.    Thomale UW, Bender M, Casalis P, Rupprecht S, Griebenow M, Neumann K, Woiciechowsky C, Unterberg AW, Stover JF.: Tacrolimus depresses local immune cell infiltration but fails to reduce cortical contusion volume in brain-injured rats. Immunobiology 2007;212(7):567-76.

52.    Griebenow M, Casalis P, Woiciechowsky C, Majetschak M, Thomale UW. Ubiquitin reduces contusion volume after controlled cortical impact injury in rats. J Neurotrauma 2007 Sep;24(9):1529-35.

53.    Stockhammer F, Plotkin M, Amthauer H, van Landeghem FK, Woiciechowsky C. Correlation of F-18-fluoro-ethyl-tyrosin uptake with vascular and cell density in non-contrast-enhancing gliomas. J Neurooncol.2008 Jun;88(2):205-10.

54. Cabraja M, Abbushi A, Costa-Blechschmidt C, van Landeghem FK, Hoffmann KT, Woiciechowsky C, Kroppenstedt S. Atypical cervical spondylotic myelopathy mimicking intramedullary tumor. Spine. 2008 Mar 15;33(6):E183-7.

55. Stummer W, Reulen HJ, Meinel T, Pichlmeier U, Schumacher W, Tonn JC, Rohde V, Oppel F, Turowski B, Woiciechowsky C, Franz K, Pietsch T; ALA-Glioma Study Group. Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias. Neurosurgery. 2008 Mar;62(3):564-76.

56. Abbushi A, Endres M, Cabraja M, Kroppenstedt SN, Thomale UW, Sittinger M, Hegewald AA, Morawietz L, Lemke AJ, Bansemer VG, Kaps C, Woiciechowsky C. Regeneration of Intervertebral Disc Tissue by Resorbable Cell-Free Polyglycolic Acid-Based Implants in a Rabbit Model of Disc Degeneration. Spine. 2008 May 23.

57. Pichlmeier U, Bink A, Schackert G, Stummer W; ALA Glioma Study Group. Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients. Neuro Oncol. 2008 Dec;10 (6):1025-34.

58. Abbushi A, Cabraja M, Thomale UW, Woiciechowsky C, Kroppenstedt SN. The influence of cage positioning and cage type on cage migration and fusion rates in patients with monosegmental posterior lumbar interbody fusion and posterior fixation. Eur Spine J. 2009 Nov;18 (11):1621-8.

59. Cabraja M, Abbushi A, Woiciechowsky C, Kroppenstedt S. The short- and mid-term effect of dynamic interspinous distraction in the treatment of recurrent lumbar facet joint pain. Eur Spine J. 2009 Nov;18 (11):1686-94.

60. Cabraja M, Abbushi A, Kroppenstedt S, Woiciechowsky C. ages with fixation wings versus cages plus plating for cervical reconstruction after corpectomy - is there any difference? Cen Eur Neurosurg. 2010 May;71(2):59-63. 

61.  Endres M, Abbushi A, Thomale UW, Cabraja M, Kroppenstedt SN, Morawietz L, Casalis PA, Zenclussen ML, Lemke AJ, Horn P, Kaps C, Woiciechowsky C.  Intervertebral disc regeneration after implantation of a cell-free bioresorbable implant in a rabbit disc degeneration model. Biomaterials. 2010 Aug;31(22):5836-41.

62. Cabraja M, Abbushi A, Koeppen D, Kroppenstedt S, Woiciechowsky C. Comparison between anterior and posterior decompression with instrumentation for cervical spondylotic myelopathy: sagittal alignment and clinical outcome. Neurosurg Focus. 2010 Mar;28(3):E15.

63. Hegewald AA, Enz A, Endres M, Sittinger M, Woiciechowsky C, Thomé C, Kaps C. Engineering of polymer-based grafts with cells derived from human nucleus pulposus tissue of the lumbar spine. J Tissue Eng Regen Med. 2010 Jul 26.

64. Hegewald AA, Endres M, Abbushi A, Cabraja M, Woiciechowsky C, Schmieder K, Kaps C, Thomé C. Adequacy of herniated disc tissue as a cell source for nucleus pulposus regeneration. J Neurosurg Spine. 2011 Feb;14(2):273-80.

65. Cabraja M, Endres M, Hegewald AA, Vetterlein S, Thomé C, Woiciechowsky C, Kaps C.: A 3D environment for anulus fibrosus regeneration. J Neurosurg Spine. 2012 Aug;17(2):177-83.

66. Woiciechowsky C, Abbushi A, Zenclussen ML, Casalis P, Krüger JP, Freymann U, Endres M, Kaps C.: Regeneration of nucleus pulposus tissue in an ovine intervertebral disc degeneration model by cell-free resorbable polymer scaffolds. J Tissue Eng Regen Med. 2012 Aug 3.

67. Hegewald AA, Zouhair S, Endres M, Cabraja M, Woiciechowsky C, Thomé C, Kaps C.: Towards biological anulus repair: TGF-β3, FGF-2 and human serum support matrix formation by human anulus fibrosus cells. Tissue Cell. 2012 Oct 31.

68. Cabraja M, Endres M, Abbushi A, Zenclussen M, Blechschmidt C, Lemke AJ, Kroppenstedt S, Kaps C, Woiciechowsky C.: Effect of degeneration on gene expression of chondrogenic and inflammatory marker genes of intervertebral disc cells: a preliminary study. J Neurosurg Sci. 2013 Dec;57(4):307-16.

69. Suchomel P, Jurák L, Antinheimo J, Pohjola J, Stulik J, Meisel HJ, Cabraja M, Woiciechowsky C, Bruchmann B, Shackleford I, Arregui R, Sola S.: Does sagittal position of the CTDR-related centre of rotation influence functional outcome? Prospective 2-year follow-up analysis. Eur Spine J. 2014 Feb 20.



1.    Woiciechowsky C and Lanksch WR: Primäre und metastatische Tumoren des Nervensystems. In Harrisons Innere Medizin, Ed.: Sagar SM and Israel M, Verlag; ABW Wissenschaftsverlag GmbH, S. 2660-2670, 2002.

2.    Volk HD, Zuckermann H, Kox W, Woiciechowsky C, Hoeflich C, Meisel C, Gruetz G, Döcke WD, Reinke P: Immune monitoring and strategies for immune modulation. In Serie: Molecular and Cellular Biology of Critical Care Medicine, Band: Immunology and infectious disease, Ed.: Doughty LA und Linden P, Verlag: Kluwer Academic Publishers, Norwell, S 155-186, 2003.

3.    Woiciechowsky C and Volk HD: Influence of brain-derived cytokines on the immune response. In Serie: Progress in Inflammation Research, Band: Mind over Matter - Regulation of peripheral inflammation. Ed.: Parnhamm MJ, Verlag: Birkhäuser AG, S. 19-33, 2003.

4.    Kneissler M, Hein A, Mätzig M, Thimble, UW, Lueth TC, Woiciechowsky C: Concept and Clinical Evaluation of Navigated Control in Spine Surgery. IEEE/ASME International Conference on  Advanced Intelligent Mechatronics (AIM). Kobe, Japan, 2003.

5.    Woiciechowsky C: Role of peripheral nerves, neurogenic inflammation. In Serie: Neuroimmune Biology. Ed.: Buckingham J and Arnason B, Verlag: Elsevier Science, 2010.